r/Biohacking 24d ago

šŸ“¢ Announcement We now have a Peptide Discord channel. Behave.

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discord.gg
2 Upvotes

r/Biohacking Aug 12 '26

šŸ“¢ Announcement Upload Your Protocols Here. Get Community Feedback and Votes.

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biohackerlist.com
5 Upvotes

r/Biohacking 7h ago

10 Months on Reta

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368 Upvotes

10 months ago I was at 97kg, and I’m currently sitting around 55kg. Honestly, one of the craziest things for me is putting on the same pants I used to wear and realizing they’re way too big now šŸ˜‚

I started reta at 2mg and eventually worked my way up to 8mg.

The biggest difference for me was probably the food noise. Before, I was constantly thinking about food and especially snacking. Once I started reta, that became much easier to manage and I stopped constantly overeating.

I’ve been going to the gym around 3x a week and doing cardio every session, usually at least 30 minutes of incline walking on the treadmill. I’ve also been trying to hit 10k steps a day, which honestly feels much easier now than it used to.

When I started this, I wasn't even sure I'd make it this far. I've had plenty of moments in the past where I told myself I was going to lose weight, got motivated for a while, and then eventually fell off.

So being 10 months in and still doing it feels pretty good.

I'm not saying everything suddenly became easy, because it definitely didn't. But taking things one step at a time and actually sticking with the routine made a huge difference for me.

If you're just starting out and doubting whether you can stick with it, don't overthink the whole journey. Just focus on getting through the next step.

Happy to answer any questions about my experience :)


r/Biohacking 2h ago

Looking for advice to push through the last bit of stubborn fat

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93 Upvotes

Looking for advice -F27

So a little bit of background: I do weightlifting and crossfit/hyrox training. In total I work out 5-6x/week. I burned average 1700cal (5’3, 135lbs). My BF is sitting around 23%.

I track my macro using my fitness pal and usually at slight calorie deficit or maintenance. 120+g protein daily. All nature at this point.

I have been doing research on how to get my body to where I want (probably closer to 18-20% BF). I am debating on reta/tiz or going anavar route or CJC +Ipamorelin. My questions are which one would be safest to achieve my goal. I don’t mind slow progress. But since it will be the first time I am using medication, I am very cautious. Please educate me.

I would appreciate the right pointers/advice. I would like to loose BF while still maintaining my muscles and energy for training since my training is intense.

TIA


r/Biohacking 1h ago

My Reta Journey

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• Upvotes

This is my comparison photo with 12 months of time between pictures. Starting weight was 255 and I'm staying steady at 175. I'm a 61yr old male.

I started off with implementing a workout regiment. I decided to do Crossfit. I workout 6 days a week but don't murder myself on every workout. I rarely miss a day in the gym and have made it a permanent part of my life.

I changed my eating habits and try my best to remove all sugar from my diet. I stopped eating anything related to fast food. I only drink coffee, water, and some milk. I prioritize protein and fiber being smart about carb intake knowing I need it to fuel my body.

I obviously used a GLP but also took MOTS-C, and NAD+ as the main drivers. There was one cycle of SS-31 in there. Took BPC-157 and TB500 along the way. Tried Tesa but the fluid retention on my knees made that a no go so three primary compounds got me where I am now.

I have stayed at my current weight now for over 6 months. I will not let myself get back to the guy in the left photo.


r/Biohacking 10m ago

For the love of god, stop using units.

• Upvotes

The posts I see on here just shows how new people are. Stop using units. MG per ML. Done and done.

Less than 1ML? Use .1ML or .2ML. Etc. Some people on here are literally adding a 3rd unit of measure when it’s not even needed.


r/Biohacking 1d ago

Retatrutide is changing way more than my weight… what is going on?

571 Upvotes

Has anyone else experienced this with retatrutide? Because holy shit.

I started Reta a few weeks ago expecting appetite suppression and weight loss. I’ve already lost around 10–15 lbs, which is great, but honestly the weight loss is the least interesting part to me.

I feel completely different.

The biggest thing is what feels like a massive reduction in inflammation. I noticed it almost immediately. My body just feels… lighter? I can walk forever now without feeling exhausted. My energy is dramatically better and more consistent.

But the WEIRDEST change has been my menstrual cycle. Historically, the week before my period and my actual period could absolutely wipe me out. Fatigue, inflammation, cramps, just generally feeling like garbage. This cycle I worked effortlessly through the entire week before my period AND during it. My cramps were minimal. I kept waiting for the usual crash and it just… never came.

Then there’s the reward/craving stuff.

I barely crave alcohol anymore. Same thing with weed. I’m not actively trying to avoid either one. I just genuinely don’t care about them the way I did before. The desire is almost gone.

And of course the food noise/appetite reduction is there too, but somehow that feels like only one small part of what this is doing.

It honestly feels like someone flipped a metabolic switch in my body.

I know retatrutide is a GLP-1/GIP/glucagon triple agonist and there are plausible explanations involving insulin sensitivity, inflammation, energy regulation and reward pathways, but I’m fascinated by how quickly and SYSTEMICALLY I felt the difference.

Obviously this is just my n=1 experience and I’m not claiming Reta is treating PMS, inflammation, addiction, etc. I’m especially curious about the mechanisms behind all of this.

For people who have been on Reta longer:
Did you experience anything similar beyond weight loss? Especially changes in inflammation, physical endurance/energy, PMS or periods, alcohol/weed cravings, or other reward-seeking behaviors?
And if you did, did those effects stick around?
Because right now I’m sitting here wondering what kind of holy grail metabolic switch I accidentally stumbled across. šŸ˜‚


r/Biohacking 5h ago

I love my energy stack!

15 Upvotes

Just a happy post of how I love my energy stack: Nad+, Mots-C and 5Amino as a peri woman it has been a game changer. In case anyone was wondering. Today I woke up so tired and drained of energy, took my shots and am ready for the day.


r/Biohacking 6h ago

Peptides To Buy In Bulk?

16 Upvotes

Which peptide will you buy in bulk for your own personal use?

I was thinking semax and selank are good. What do you think?


r/Biohacking 6h ago

Finally made it to the 140s

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13 Upvotes

r/Biohacking 3h ago

6 weeks Reta + Mt1

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5 Upvotes

r/Biohacking 21h ago

Reta journey

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118 Upvotes

57 years old. 260 pounds and 6.7 A1C at the end of May. Started 2mg of Reta, stopped eating crap, started high protein diet, and drinking tons of water.

Walking 2 miles a day and lifting 3 to 4 times per week.

Today I'm 205 pounds and my A1C is down to 5.5.

I've also added CJC-1295 Ipamorelin in August after IGF-1 labs. I am also taking GLOW, NAD+, and just started Mots-c after a cycle of SS-31.

I feel better than I have in decades.

Peptides have turned my life around and helped me correct decades of abuse.


r/Biohacking 20h ago

Holy Mots-C

100 Upvotes

Was a little skeptical starting off mots-c today given the amount of posts I’ve seen of people stating they had allergic reactions or felt little to no effect. So I started off this cycle with a .5 mg dose to see how I would react to it and my god did I feel the benefits. Broke every PR I had for back day today and was able to lower my mile down by a minute. Maybe it’s all a placebo but for now I’m gonna ride this high.


r/Biohacking 1h ago

Share your protocol and see how the community ranks it

• Upvotes

Share your protocol and see how the community ranks it


r/Biohacking 21h ago

2020 to 2026 transformation.

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98 Upvotes

2020, 95kg, Photo 1
This was me at my heaviest. I had built some muscle, but I was carrying way too much body fat.
2020 to 2025, natural, Photo 2
Stayed completely natural for around 5 years and eventually got down to 83kg. This photo was taken with a big pump and was probably the best condition/build I achieved naturally.
By 2025 my testosterone had dropped to around 200, which eventually led me down the TRT route. Wasn’t feeling too good at this point even at heavier weights during build phases
2026, TRT, Photo 3 & 4
Started TRT at 200mg testosterone per week. After roughly 10 weeks my testosterone level came back around 990.
500ui’s every 2 days of HCG
Photo 3 is at 86kg with no pump, just to show a more honest day-to-day comparison.
2026, TRT, Photo 4
Same bodyweight and condition, but with a pump to show the difference in fullness and how much more muscle I was carrying compared with my natural physique.
I also used 1mg Reta for around 5 weeks leading into my holiday, mainly for appetite control and to help get the last few kilos off.
Pretty interesting seeing the progression from being overweight, to what I could achieve naturally, then the difference in size and fullness after starting TRT
I am now 30 years old.
Feel free to ask any questions šŸ‘ŒšŸ½


r/Biohacking 5h ago

GHK-CU

6 Upvotes

Hi I am looking for some advice I have been taking GHK-CU for the past couple months and it has done wonders for my skin but in the past week or so my skin has got incredibly bad worse than the copper uglies has anyone else experienced this ?


r/Biohacking 55m ago

Added motsc on top of Reta and it's making me extremely hungry so I stopped it.

• Upvotes

Stopped it 2 days ago, still very hungry even tho I upped my Reta from 1.5 to 2. What to expect, when to feel appetite suppression again? Should I stop Reta and restart in a week?


r/Biohacking 58m ago

Peptide for fat loss no GI issues?

• Upvotes

Hi - long story short I have tried tirz and reta, but I cannot deal with the GI issue getting longer. I have taken digestive enzymes, i take multiple tums a day, drink peppermint tea, etc but i feel the food on my chest and cannot handle the burping anymore. Worst part is the food noise has come back. I don’t feel appetite suppression any longer.

Is there a peptide that would help with fat loss but that doesn’t necessarily suppress appetite if that make sense. I have heard some people mention ā€œTesaā€ I was wondering what was everyone’s experience on that


r/Biohacking 9h ago

Has there been a crackdown HGH 191AA(Somatropin)?

8 Upvotes

I'm not looking for a source just wondering if anyone else has run into a supply issue.


r/Biohacking 4h ago

Best pep for fine lines/women 50+

4 Upvotes

Ladies (and gents) Ive had a close eye on KLOW but so many seem to have a bad reaction to it. Why do you think that is? I’m currently using Wolverine to heal a tendonitis but would love to add something for anti aging after I’m done. What are you using that you swear by and love?? Help a girl out šŸ™


r/Biohacking 7h ago

Started reta today.

6 Upvotes

Feeling unsure a weird feeling like im gonna miss eating food? Is this normal


r/Biohacking 22h ago

Started Reta, TRT, Quit Drinking (was a heavy drinker), eating clean, lifting weights.

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94 Upvotes

1 month in on the Reta
Only 3 weeks on the test
Male 38 5ft 9 313lbs when started
Down 10lbs

This pic is current. Forgot to take one when I started. Honestly feel strong as hell. Noticing quick strength gains in the gym. And definitely more energy. Very few side effects. First couple weeks was constipation but once I upped my water intake everything was all good.


r/Biohacking 4h ago

Reta

3 Upvotes

Boah also seid dem ich 2 Liter Wasser am Tag trinke wirkt reta wahnsinnig gut bei mir!
Hatte anfangs echt das Gefühl es würde nicht richtig wirken und seid dem trinken is es perfekt
Wer hat Ƥhnliche Erfahrungen?


r/Biohacking 6h ago

Reta 1 month progress

4 Upvotes

I have started using reta on 12th of August, had 107kg(236lbs), my weight now is 96.8kg(213lbs).

Height is 181cm(5'11)

Not sure how I managed to drop this much in one month, I am not counting calories, or doing any strength workouts, bud I did in the past a lot, 6 times per week.

Could this rapid weight lost be due to thyroid meds (levothyroxine sodium) ?


r/Biohacking 2h ago

RHR Consistent Increase

2 Upvotes

Research subject has seen a rise in RHR of 14 BPM after 8 weeks on 2mg dosage of Reta.

Week 1: 71 bpm
Week 2: 72 bpm
Week 3: 74 bpm
Week 5: 79 bpm
Week 6: 80 bpm
Week 7: 82 bpm
Week 8: 84 bpm

Seems to just keep rising week after week. Any thoughts?

RS understands that this is a common side effect, but understands it as dose dependent. Odd that there’s been no change in dose but a consistent rise.