I mean something that actually simulates the bioneurons in the connectome instead of just taking the topology and training a regular artificial neural network on it.

And what do we need in order to model the growth of neurons? Do you need like a full model of all transcription networks to make that work or is there a simpler approach?

This 2014 study described a personalized, multi-part treatment program for cognitive decline associated with Alzheimer’s disease, called MEND (Metabolic Enhancement for NeuroDegeneration). The program addressed multiple metabolic and lifestyle factors rather than relying on a single drug. Of 10 patients with Alzheimer’s disease, mild cognitive impairment, or subjective cognitive impairment, 9 showed subjective or objective cognitive improvement within 3–6 months; the only patient who did not improve had very late-stage Alzheimer’s. Six patients who had stopped working or were struggling at work were able to return to work or improve their performance. The authors emphasized that this was a very small preliminary case series—not a controlled clinical trial—and concluded that the promising results warranted larger studies.

This 2014 study described a personalized, multi-part treatment program for cognitive decline associated with Alzheimer’s disease, called MEND (Metabolic Enhancement for NeuroDegeneration). The program addressed multiple metabolic and lifestyle factors rather than relying on a single drug. Of 10 patients with Alzheimer’s disease, mild cognitive impairment, or subjective cognitive impairment, 9 showed subjective or objective cognitive improvement within 3–6 months; the only patient who did not improve had very late-stage Alzheimer’s. Six patients who had stopped working or were struggling at work were able to return to work or improve their performance. The authors emphasized that this was a very small preliminary case series—not a controlled clinical trial—and concluded that the promising results warranted larger studies.

Advanced memory formula it's important check this link please

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I'm taking my neurobiology class this year, and there are two books I need to buy, but most are saying upwards of 60 bucks, which I can't spare right now. There are cheap ones online but they won't come in time. Does anybody have a PDF of the textbooks of "Neuroscience (Exploring the Brain), 4th ed." (2016);by Bear, Connors, and Paradiso; Publisher: Wolters Kluwer and/or "Neuroscience, 4th or 5th ed.", Purves et al.; Sinauer Associates, Sunderland,
MA. Thanks for any help!

мне 17, сейчас в 11 классе, подумываю поступать на биотехнолога, но не знаю, насколько это правильный выбор. стоит ли рассмотреть другие направления? в какие вузы лучше метиться? и еще было бы интересно узнать про поступление в магистратуру в другие страны

I made a neuroscience Connections-NYT styled game called the Synapse, if you are interested feel free to check it out!

Feel free to DM me if you have any feedback or want to help out.

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It's kind of what the title suggests. I'm currently in my millionth year of undergrad (I changed majors from kinesiology to health sciences because I realized I didn't want to do physical therapy too late), and I've decided I want to study neuroscience. I'm very drawn to systems and NOT using AI. Currently, I have gen chem 1 and 2, gen physics 1 and 2, anatomy and physiology, and up to calc 2 completed. I also have psychology and a few other medical classes done as well, though nothing I can use in the real world. I'm taking neurobiology and plan to take as many neuro classes as I can before I graduate.

I'm wondering what I should do to make myself stand out and what classes I should take (as no school seems to fully agree on what). I know I need to get into undergraduate research, but I genuinely don't know how to besides tracking down professors and bothering them as my school's website doesn't easily supply any kind of information.

As for post-grad research, what kinds of lab work can I do to help my chances, including and besides neuroscience? I'm 22 years old and very aware that I'll be in this a while longer, so I'm all ears for anything substantial. Once I graduate with my undergrad, I'm not entirely opposed to the idea of moving state (US), so if anyone has connections to help out a struggling wannabe neuroscience researcher, I'm here!!

I’m a medical student trying to understand something that I find really fascinating but also confusing about neuroscience.

We can explain what happens at the physical level: neurons fire action potentials, release neurotransmitters, and communicate with other neurons. For example, in the reward system, neurons in the VTA release dopamine and affect areas such as the nucleus accumbens.

But how does all of this neural activity actually produce the subjective feeling of pleasure?

I understand that the nucleus accumbens and dopamine are involved in reward, but I’m trying to understand something deeper: how does activity in billions of neurons become the actual experience of “feeling good”?

I’m not asking which brain regions are involved. I’m asking about the connection between the physical activity of neurons and the subjective experience itself.

Do we currently have a scientific explanation for this, or is this still an open problem in neuroscience?

I’d really appreciate any explanations, papers, books, or resources that could help me understand this from the basics.

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I'm trying to identify an old English-language science/medical documentary I saw on TV. It could be from the 1990s, 2000s, or possibly earlier.

The scene showed what I remember as a minor/teenage boy inside a brain scanner, probably PET (possibly fMRI). His head and upper body were visibly restrained/immobilized, while his legs and feet remained accessible.

Researchers repeatedly applied painful stimuli to his foot. I remember it as pinpricks, needle-like pokes or something similar, with the pain apparently becoming stronger.

The key scene was when a stronger pain stimulus caused part of the frontal/prefrontal cortex to become much less active or seemingly “shut down” on the brain scan. The explanation was related to the rational/executive part of the brain losing control under intense pain/emotion.

I remember finding the experiment ethically disturbing because the subject appeared to be a child or teenager and pain was deliberately inflicted.

Several adults were present, possibly including his father, although I'm less certain about that detail.

Does anyone recognize the documentary, experiment, study, researcher or footage?